Like VV1, the game is left 'open-ended'. If you don't want to continue searching for the least few collectibles you can start another game or let your villagers carry on as they are, and pop in every now and then to see how they're getting on. Of course, you can always start another game in another slot, while keeping the first game running.
Every game played is different and you can try out different strategies to see how they affect your villagers' development.
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To err is human; to arr is pirate.