In one game, I work on making every villager at least an adept Builder, Healer and Farmer (and the women Parents.) I've run into a few stubborn villagers that really resist learning certain skills.
Most of the games that I keep running I'll just check in every day to see new events and make sure that there is at least one male parent to keep the tribe going. But they may be at diffwerent speeds and different levels of difficulty.
I have two games where they are GC free! One read the Book of Peals, the other followed the face in the woods.
Occasionally, I'll start a new game with a particular goal from the beginning. One Easy game I wanted to see if I could finish it without checking any skill as preferred, and just letting the villagers do what they want with a bit of nudging.
I have one game running where I don't have Level 3 Fishing. The tribe is surviving, but with the GC's help. It's also the game where I have my highest mushroom count! (now ranked #3!)
I know others have succeeded in finishing all of the puzzles except for the graveyard. I haven't managed that, becuase I always ended up with a bad event that caused fatal problems.
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Isola is a magic island! All sorts of strange things can happen, and often do happen. -- arnie