I think that I would agree on the dream event. Or events that give me a master researcher after I have level 3 in all of the tech.
I don't mind losing all of the food, as Monk said, it doesn't take long to get it back, especially if the GC is helping replensih the berries and crops.
I don't like losing Tech or a villager at the beginning of a game. I still feel bad for poor Cheop, the last of his tribe.

In the hard game that replaced Cheop's tribe, I lost two kids at a critical time (one was 12 the other just turned 14...) I was waiting for them to be old enough to help work at the research table.
