I'll generally try to look at each child's adoption screen at least twice before deciding, based mainly on their money-making potential and preferences for kids. In my last game I looked through each screen of the six kids about five times. It was so difficult to choose between them that I ended up picking one of them almost at random.
Me to for the most part.
there have ben occasions though when I've decided on a girl one time and boy the next for a few generations, but generally I pick the best earners and preference for kids. Two who definitely don't want children can be a real pain in the butt. Making for a slow and frustrating game.
I have, on occasion though changed myh little peep's careers. Occasionally one just will NOT work on their career, despite several praises and sweeties etc., I guess they've just ot been happy with their lot in life.
If that's the case and the opportunity presents itself I will change them.
If I end up with a couple who don't really get along much, don't like to work, and won't build up much cash in which to move the game on, I'll feed them only on the bargain smart price foods. short life, I know but times must.....lol