I always try to get them to have children as long as they haven't had their full 6 yet.. even in their late 50's

I do run into problems with having children in the late 40's, but like namesdi mentioned you never know what could happen!
If you do have a child when your peeps are older, you may run into the situation of the child being left alone while the two parents pass away. You can choose to start the new generation, or you can choose to watch the little child grow up you would just have to be creative on feeding, putting groceries away and other adult tasks.