OK, then the next thing to do is part 2 of my earlier post, which should fix the uneditable file situation:
If that doesn't work, you should completely uninstall Virtual Families again, reinstall the game, only this time do not let the game run immediately after installing it. Uncheck both of those check boxes, and close the installer. Then run the game and see if it will launch properly (in full screen). Leave it in full screen, quit the game and try to launch it again to see if it still works.