I have a little problem, i hope someone can help me solve this. I have done 52 potions, how come it still doesn't solve the completed puzzle. do i have to do more or what seems to be the problem?

It depends..

Have you done a certian potion more than once? Doubles do not count for that award.

i was marking them, one by one.. so i wouldn't do that mistake.

Did you ever have a time when a potion failed? If so, those don't count in the total. It's also possible to get the herbs mixed up (or even overlap them, if you're not very careful). That will cause problems with keeping track, too.

Luckly I haven't had no explosion, since i started to do my potions until I bought all of alchemy. I was carfully selecting the herbs, but maybe i wasn't to careful.

Not a single explosion in 52 potions? Your luck is, incredible, sir, in the hard-to-credit sense of incredible. Unless you went to Alchemy 3 before you started mixing a single potion.

I think that's the case, Lurkily, if I understand this comment correctly:

Meh. You're right. Reading is fundamental, so I guess I'm fundamentally flawed.

Maybe you did the same herbs in a different order - for example rose + rose + orchid is the same as rose + orchid + rose.

That happened to me!

I did 112, but when I did 211 it blew up. so did 212. do they randomly blow up or is that potion going to blow up every time?

They blow up randomly as far as I know. If you try that potion again, it won't necessarily blow up, but it may blow up a number of times in a row, or it may work perfectly fine.

To eliminate the risk of potions blowing up, you will want your alchemy up to level 3

Explosions are totally, completely random. There is no potion, not a single one, that requires alchemy. I've finished every puzzle in the game, and the alchemy challenge, with Alchemy 1.

Potion 112, 212, and 211 are all the same potion, and all three together count only once towards the 52-potion total.

do the villagers have to use the potion?.. or can i just make the potion without having anyone taste it? to complted the 50 recipes?

Wrong.

212 has 2 twos and 1 one

112 and 211 have 2 ones and 1 two

No. So long as it is completed successfully without blowing up, it will count as one of your 50.