I don't have the patience to try for this award normally but I went for it with one village just so that I could say it had been gained.

I printed out one of the potions lists, then marked off each herb needed as it was collected, as well as when the potion itself was brewed. I only got the villagers to try some of the more amusing potions. I left the harmful ones to last (in case I accidentally fed some to a villager) and kept checking the awards page to see if I'd reached the magic 50 yet. When it did appear I stopped, so I've never made all the possible potions.